Insights on Cytochrome P450 Enzymes and Inhibitors Obtained Through QSAR Studies

The cytochrome P450 (CYP) superfamily of heme enzymes play an important role in the metabolism of a large number of endogenous and exogenous compounds, including most of the drugs currently on the market. Inhibitors of CYP enzymes have important roles in the treatment of several disease conditions s...

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Bibliographic Details
Main Authors: Maryam Foroozesh, Cheryl L. Klein Stevens, Jiawang Liu, Jayalakshmi Sridhar
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Molecules
Subjects:
SAR
Online Access:http://www.mdpi.com/1420-3049/17/8/9283