Age Is Relative—Impact of Donor Age on Induced Pluripotent Stem Cell-Derived Cell Functionality

Age Is Relative—Impact of Donor Age on Induced Pluripotent Stem Cell-Derived Cell Functionality

Induced pluripotent stem cells (iPSCs) avoid many of the restrictions that hamper the application of human embryonic stem cells: limited availability of source material due to legal restrictions in some countries, immunogenic rejection and ethical concerns. Also, the donor’s clinical phenotype is of...

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Bibliographic Details
Main Authors: Elisabeth Tamara Strässler, Katriina Aalto-Setälä, Mostafa Kiamehr, Ulf Landmesser, Nicolle Kränkel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
induced pluripotent stem cells
aging
senescence
cell therapy
cellular reprogramming
Online Access:http://journal.frontiersin.org/article/10.3389/fcvm.2018.00004/full

Internet

http://journal.frontiersin.org/article/10.3389/fcvm.2018.00004/full

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