Retroviral DNA integration: viral and cellular determinants of target-site selection.

Retroviral DNA integration: viral and cellular determinants of target-site selection.

Retroviruses differ in their preferences for sites for viral DNA integration in the chromosomes of infected cells. Human immunodeficiency virus (HIV) integrates preferentially within active transcription units, whereas murine leukemia virus (MLV) integrates preferentially near transcription start si...

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Bibliographic Details
Main Authors: Mary K Lewinski, Masahiro Yamashita, Michael Emerman, Angela Ciuffi, Heather Marshall, Gregory Crawford, Francis Collins, Paul Shinn, Jeremy Leipzig, Sridhar Hannenhalli, Charles C Berry, Joseph R Ecker, Frederic D Bushman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1480600?pdf=render

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http://europepmc.org/articles/PMC1480600?pdf=render

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