Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses.

Herpesvirus Genome Recognition Induced Acetylation of Nuclear IFI16 Is Essential for Its Cytoplasmic Translocation, Inflammasome and IFN-β Responses.

The IL-1β and type I interferon-β (IFN-β) molecules are important inflammatory cytokines elicited by the eukaryotic host as innate immune responses against invading pathogens and danger signals. Recently, a predominantly nuclear gamma-interferon-inducible protein 16 (IFI16) involved in transcription...

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Bibliographic Details
Main Authors: Mairaj Ahmed Ansari, Sujoy Dutta, Mohanan Valiya Veettil, Dipanjan Dutta, Jawed Iqbal, Binod Kumar, Arunava Roy, Leela Chikoti, Vivek Vikram Singh, Bala Chandran
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1005019

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https://doi.org/10.1371/journal.ppat.1005019

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