C2 Domains as Protein-Protein Interaction Modules in the Ciliary Transition Zone
RPGR-interacting protein 1 (RPGRIP1) is mutated in the eye disease Leber congenital amaurosis (LCA) and its structural homolog, RPGRIP1-like (RPGRIP1L), is mutated in many different ciliopathies. Both are multidomain proteins that are predicted to interact with retinitis pigmentosa G-protein regulat...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-07-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714004434 |