Investigation of molecular mechanisms of experimental compounds in murine models of chronic allergic airways disease using synchrotron Fourier-transform infrared microspectroscopy

Abstract The ovalbumin-induced (OVA) chronic allergic airways murine model is a well-established model for investigating pre-clinical therapies for chronic allergic airways diseases, such as asthma. Here, we examined the effects of several experimental compounds with potential anti-asthmatic effects...

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Bibliographic Details
Main Authors: Nadia Mazarakis, Jitraporn Vongsvivut, Keith R. Bambery, Katherine Ververis, Mark J. Tobin, Simon G. Royce, Chrishan S. Samuel, Kenneth J. Snibson, Paul V. Licciardi, Tom C. Karagiannis
Format: Article
Language:English
Published: Nature Publishing Group 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-68671-2