Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes

Maternal gene Ooep may participate in homologous recombination-mediated DNA double-strand break repair in mouse oocytes

DNA damage in oocytes can cause infertility and birth defects. DNA double-strand breaks (DSBs) are highly deleterious and can substantially impair genome integrity. Homologous recombination (HR)-mediated DNA DSB repair plays dominant roles in safeguarding oocyte quantity and quality. However, little...

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Bibliographic Details
Main Authors: Da-Jian He, Lin Wang, Zhi-Bi Zhang, Kun Guo, Jing-Zheng Li, Xie-Chao He, Qing-Hua Cui, Ping Zheng
Format: Article
Language:English
Published: Science Press, PR China 2018-11-01
Series:Zoological Research
Subjects:
Ooep
Homologous recombination
DNA double-strand break repair
ATM
RAD51
Online Access:http://www.zoores.ac.cn/EN/abstract/abstract3900.shtml

Internet

http://www.zoores.ac.cn/EN/abstract/abstract3900.shtml

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