TOP2A and CENPF are synergistic master regulators activated in cervical cancer

TOP2A and CENPF are synergistic master regulators activated in cervical cancer

Abstract Background Identification of master regulators (MRs) using transcriptome data in cervical cancer (CC) could help us to develop biomarkers and find novel drug targets to fight this disease. Methods We performed differential expression (DE) analyses of public microarray and RNA-seq transcript...

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Bibliographic Details
Main Authors: Beiwei Yu, Long Chen, Weina Zhang, Yue Li, Yibiao Zhang, Yuan Gao, Xianlin Teng, Libo Zou, Qian Wang, Hongtao Jia, Xiangtao Liu, Hui Zheng, Ping Hou, Hongyan Yu, Ying Sun, Zhiqin Zhang, Ping Zhang, Liqin Zhang
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Medical Genomics
Subjects:
Cervical cancer
Master regulator
Transcriptome
Differential expression
Differential activity
Online Access:http://link.springer.com/article/10.1186/s12920-020-00800-2

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http://link.springer.com/article/10.1186/s12920-020-00800-2

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