Distinct Pharmacological Properties of Gaseous CO and CO-Releasing Molecule in Human Platelets

Distinct Pharmacological Properties of Gaseous CO and CO-Releasing Molecule in Human Platelets

Carbon monoxide (CO)—gaseous or released by CO-RMs—both possess antiplatelet properties; however, it remains uncertain whether the mechanisms involved are the same. Here, we characterise the involvement of soluble guanylate cyclase (sGC) in the effects of CO—delivered by gaseous CO–saturated buffer...

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Bibliographic Details
Main Authors: Patrycja Kaczara, Kamil Przyborowski, Tasnim Mohaissen, Stefan Chlopicki
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
platelet aggregation
carbon monoxide
soluble guanylate cyclase
energy metabolism
CO-RMs
Online Access:https://www.mdpi.com/1422-0067/22/7/3584

Internet

https://www.mdpi.com/1422-0067/22/7/3584

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