PODOCYTE-SPECIFIC OVEREXPRESSION OF SIRT-1 INCREASES NEPHRIN IN OBESE MICE FED A HIGH-FAT DIET
Obesity can lead to inflammation, hyperlipidemia, diabetes, hypertension, and renal dysfunction, and is also associated with proteinuria. Histopathological changes in the glomeruli in obesity were characterized by glomerulomegaly and focal segmental glomerulosclerosis. This study was designed to inv...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
The Korean Society of Nephrology
2012-06-01
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| Series: | Kidney Research and Clinical Practice |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211913212004275 |