Association of FcγRIIa R131H polymorphism with idiopathic pulmonary fibrosis severity and progression

<p>Abstract</p> <p>Background</p> <p>A significant genetic component has been described for idiopathic pulmonary fibrosis (IPF). The R131H (rs1801274) polymorphism of the IgG receptor FcγRIIa determines receptor affinity for IgG subclasses and is associated with several...

Full description

Bibliographic Details
Main Authors: Hirani Nikhil, McFarlane Pauline, Wallace William A, Murchison John T, Alexander Karen M, Grinfeld Jacob, Bournazos Stylianos, Simpson A John, Dransfield Ian, Hart Simon P
Format: Article
Language:English
Published: BMC 2010-10-01
Series:BMC Pulmonary Medicine
Online Access:http://www.biomedcentral.com/1471-2466/10/51