A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network

Planar cell polarity (PCP) requires the asymmetric sorting of distinct signaling receptors to distal and proximal surfaces of polarized epithelial cells. We have examined the transport of one PCP signaling protein, Vangl2, from the trans Golgi network (TGN) in mammalian cells. Using siRNA knockdown...

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Bibliographic Details
Main Authors: Yusong Guo, Giulia Zanetti, Randy Schekman
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2013-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/00160