DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer

DNA Polymerase Alpha Subunit B Is a Binding Protein for Erlotinib Resistance in Non-Small Cell Lung Cancer

Erlotinib inhibits epithelial growth factor receptor (EGFR) kinase activity and is used to treat non-small cell lung cancer (NSCLC). Despite its high efficacy, recurrence can occur in patients who become resistant to the drug. To address the underlying mechanism of Erlotinib resistance, we investiga...

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Bibliographic Details
Main Authors: Tae Young Kim, Eun Sun Ji, Ju Yeon Lee, Jin Young Kim, Jong Shin Yoo, A. Marcell Szasz, Balazs Dome, Gyorgy Marko-Varga, Ho Jeong Kwon
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:Cancers
Subjects:
Erlotinib
POLA2
DARTS LC-MS/MS
resistance
NSCLC
Online Access:https://www.mdpi.com/2072-6694/12/9/2613

Internet

https://www.mdpi.com/2072-6694/12/9/2613

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