Differential Effect of Amyloid Beta1-40 on Short-term and Long-term Plasticity in Dentate Gyrus of a Rat Model of Alzheimer Disease

Introduction: Synaptic plasticity is inappropriately affected by neurodegenerative diseases, including Alzheimer Disease (AD). In this study, we examined the effect of intrahippocampal amyloid-beta (Aβ1-40) on dentate gyrus Long-term Potentiation (LTP) and presynaptic short-term plasticity in a rat...

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Bibliographic Details
Main Authors: Javad Fahanik-Babaei, Tourandokht Baluchnejadmojarad, Mehrdad Roghani
Format: Article
Language:English
Published: Iran University of Medical Sciences 2020-07-01
Series:Basic and Clinical Neuroscience
Subjects:
Online Access:http://bcn.iums.ac.ir/article-1-1205-en.html