A 22-amino-acid peptide regulates tight junctions through occludin and cell apoptosis
Occludin is a structural protein of tight junctions (TJ) in the blood–testis barrier (BTB). A 22-amino-acid peptide (22AA) in the second extracellular loop can reversibly regulate TJ, but its regulatory mechanism is unknown. In this study, a 22AA-induced TJ destruction animal model was constructed t...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2020-11-01
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Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/10147.pdf |