Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer

Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer

Abstract Background Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer with highly invasive ability and metastatic nature to the lymph nodes. Long non-coding RNAs (lncRNAs) have been widely explored in cancer tumorigenesis and progression. However, their roles in TNB...

Full description

Bibliographic Details
Main Authors: Shaoquan Zheng, Lu Yang, Yutian Zou, Jie-ying Liang, Peng Liu, Guanfeng Gao, Anli Yang, Hailin Tang, Xiaoming Xie
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Hematology & Oncology
Subjects:
Triple-negative breast cancer
Lymph node metastasis
Long non-coding RNA
Y-box binding protein 1
Forkhead box k1
Online Access:http://link.springer.com/article/10.1186/s13045-020-00852-y

Internet

http://link.springer.com/article/10.1186/s13045-020-00852-y

Similar Items