Plasticity of High-Density Neutrophils in Multiple Myeloma is Associated with Increased Autophagy Via STAT3

Plasticity of High-Density Neutrophils in Multiple Myeloma is Associated with Increased Autophagy Via STAT3

In both monoclonal gammopathy of uncertain significance (MGUS) and multiple myeloma (MM) patients, immune functions are variably impaired, and there is a high risk of bacterial infections. Neutrophils are the most abundant circulating leukocytes and constitute the first line of host defense. Since l...

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Bibliographic Details
Main Authors: Fabrizio Puglisi, Nunziatina Laura Parrinello, Cesarina Giallongo, Daniela Cambria, Giuseppina Camiolo, Claudia Bellofiore, Concetta Conticello, Vittorio Del Fabro, Valerio Leotta, Uros Markovic, Giuseppe Sapienza, Alessandro Barbato, Silvia Scalese, Daniele Tibullo, Maria Violetta Brundo, Giuseppe Alberto Palumbo, Francesco Di Raimondo, Alessandra Romano
Format: Article
Language:English
Published: MDPI AG 2019-07-01
Series:International Journal of Molecular Sciences
Subjects:
neutrophil
autophagy
IFN-γ
STAT-3
ruxolitinib
Online Access:https://www.mdpi.com/1422-0067/20/14/3548

Internet

https://www.mdpi.com/1422-0067/20/14/3548

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