Synthesis and cytotoxicity evaluation of thiosemicarbazones and their thiazole derivatives

ABSTRACT The aims of this study were to synthesize a series of thiosemicarbazones and their thiazole derivatives, to investigate their cytotoxic activity against three human cancers and normal (Vero cells) cell lines, and to evaluate the pro-apoptotic potential of the most active compounds. Material...

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Bibliographic Details
Main Authors: Saulo Feheiberg Pinto Braga, Nayara Cristina Fonseca, Jonas Pereira Ramos, Elaine Maria de Souza-Fagundes, Renata Barbosa de Oliveira
Format: Article
Language:English
Published: Universidade de São Paulo
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502016000200299&lng=en&tlng=en