High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma

High methylation levels of PCDH10 predict poor prognosis in patients with pancreatic ductal adenocarcinoma

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies and is not a clinically homogeneous disease, but subsets of patients with distinct prognosis and response to therapy can be identified by genome-wide analyses. Mutations in major PDAC driver genes were...

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Bibliographic Details
Main Authors: Maria Cristina Curia, Fabiana Fantini, Rossano Lattanzio, Francesca Tavano, Francesco Di Mola, Mauro Piantelli, Pasquale Battista, Pierluigi Di Sebastiano, Alessandro Cama
Format: Article
Language:English
Published: BMC 2019-05-01
Series:BMC Cancer
Subjects:
Pancreatic ductal adenocarcinoma
Epigenetics
Protocadherins
PCDH10
DNA methylation
Survival
Online Access:http://link.springer.com/article/10.1186/s12885-019-5616-2

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http://link.springer.com/article/10.1186/s12885-019-5616-2

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