Strategies for monitoring and combating resistance to combination kinase inhibitors for cancer therapy
Abstract Targeted therapies such as kinase inhibitors and monoclonal antibodies have dramatically altered cancer care in recent decades. Although these targeted therapies have improved patient outcomes in several cancer types, resistance ultimately develops to these agents. One potential strategy pr...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-04-01
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Series: | Genome Medicine |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13073-017-0431-3 |