Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

Mitochondria transfer enhances proliferation, migration, and osteogenic differentiation of bone marrow mesenchymal stem cell and promotes bone defect healing

Abstract Background Bone marrow-derived mesenchymal stem cell (BMSC) transplantation is considered a promising therapeutic approach for bone defect repair. However, during the transplantation procedure, the functions and viability of BMSCs may be impaired due to extended durations of in vitro cultur...

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Bibliographic Details
Main Authors: Yusi Guo, Xiaopei Chi, Yifan Wang, Boon Chin Heng, Yan Wei, Xuehui Zhang, Han Zhao, Ying Yin, Xuliang Deng
Format: Article
Language:English
Published: BMC 2020-06-01
Series:Stem Cell Research & Therapy
Subjects:
Mitochondria
Mitochondria transfer
BMSC function
Proliferation
Stem cell migration
Osteogenic differentiation
Online Access:http://link.springer.com/article/10.1186/s13287-020-01704-9

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http://link.springer.com/article/10.1186/s13287-020-01704-9

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