Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing.

Characterization of hepatocellular adenoma and carcinoma using microRNA profiling and targeted gene sequencing.

BACKGROUND:Hepatocellular adenomas (HCA) are benign liver tumors that may transform into hepatocellular carcinoma (HCC), but the molecular drivers of this transformation remain ill-defined. This study evaluates the molecular changes in HCA and HCC and in comparison to their adjacent non-neoplastic l...

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Bibliographic Details
Main Authors: Jian Zheng, Eran Sadot, Joana A Vigidal, David S Klimstra, Vinod P Balachandran, T Peter Kingham, Peter J Allen, Michael I D'Angelica, Ronald P DeMatteo, William R Jarnagin, Andrea Ventura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6063411?pdf=render

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http://europepmc.org/articles/PMC6063411?pdf=render

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