Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.

Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease (CAD). We have previously identified genetic linkage to familial CAD in the genomic region of NPY. We performed follow-up genetic, biostatistical, and functional analysis of NPY in early-onset CAD. In familial CAD (GENECARD,...

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Main Authors: Svati H Shah, Neil J Freedman, Lisheng Zhang, David R Crosslin, David H Stone, Carol Haynes, Jessica Johnson, Sarah Nelson, Liyong Wang, Jessica J Connelly, Michael Muehlbauer, Geoffrey S Ginsburg, David C Crossman, Christopher J H Jones, Jeffery Vance, Michael H Sketch, Christopher B Granger, Christopher B Newgard, Simon G Gregory, Pascal J Goldschmidt-Clermont, William E Kraus, Elizabeth R Hauser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC2602734?pdf=render