Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells

Ticagrelor and clopidogrel suppress NF-κB signaling pathway to alleviate LPS-induced dysfunction in vein endothelial cells

Abstract Background Ticagrelor and clopidogrel, P2Y12 receptor antagonists, can prevent thrombotic events and are used to treat cardiovascular diseases such as acute coronary syndrome and chronic obstructive pulmonary disease, in which inflammation is involved. Moreover, NF-B is the central regulato...

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Bibliographic Details
Main Authors: Zhuyin Jia, Yiwei Huang, Xiaojun Ji, Jiaju Sun, Guosheng Fu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:BMC Cardiovascular Disorders
Subjects:
Ticagrelor
Clopidogrel
LPS-induced dysfunction
NF-ΚB signaling pathway
HUVECs
Online Access:https://doi.org/10.1186/s12872-019-01287-1

Internet

https://doi.org/10.1186/s12872-019-01287-1

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