Antibody-drug conjugates in clinical trials for lymphoid malignancies and multiple myeloma

Abstract Antibody-drug conjugates (ADC) represent a distinct family of chemoimmunotherapy agents. ADCs are composed of monoclonal antibodies conjugated to cytotoxic payloads via specialized chemical linkers. ADCs therefore combine the immune therapy with targeted chemotherapy. Due to the distinct bi...

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Bibliographic Details
Main Authors: Bo Yu, Delong Liu
Format: Article
Language:English
Published: BMC 2019-09-01
Series:Journal of Hematology & Oncology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13045-019-0786-6