The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia

The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia

The serotonin transporter length polymorphism (5-HTTLPR) short allele (5-HTTLPR-s) has been associated with differential susceptibility for anxiety and depression in multiple psychiatric disorders. 5-HTTLPR-s modifies the serotonergic systems that support emotion and behavioral regulation by reducin...

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Bibliographic Details
Main Authors: Jennifer S. Yokoyama, Luke W. Bonham, Virginia E. Sturm, Babu Adhimoolam, Anna Karydas, Giovanni Coppola, Bruce L. Miller, Katherine P. Rankin
Format: Article
Language:English
Published: Elsevier 2015-01-01
Series:NeuroImage: Clinical
Subjects:
Serotonin transporter gene
Frontotemporal dementia
Structural MRI
Emotion
Amygdala
Neurodegeneration
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158215001400

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http://www.sciencedirect.com/science/article/pii/S2213158215001400

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