Predicting protein-ligand binding residues with deep convolutional neural networks

Predicting protein-ligand binding residues with deep convolutional neural networks

Abstract Background Ligand-binding proteins play key roles in many biological processes. Identification of protein-ligand binding residues is important in understanding the biological functions of proteins. Existing computational methods can be roughly categorized as sequence-based or 3D-structure-b...

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Bibliographic Details
Main Authors: Yifeng Cui, Qiwen Dong, Daocheng Hong, Xikun Wang
Format: Article
Language:English
Published: BMC 2019-02-01
Series:BMC Bioinformatics
Subjects:
Protein
Binding residues
Sequence-based methods
3D-structure-based methods
Deep convolutional networks
Online Access:http://link.springer.com/article/10.1186/s12859-019-2672-1

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http://link.springer.com/article/10.1186/s12859-019-2672-1

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