Circ_0057558 promotes nonalcoholic fatty liver disease by regulating ROCK1/AMPK signaling through targeting miR-206

Abstract Nonalcoholic fatty liver disease (NAFLD) is one of the most prevalent chronic liver disorders that is featured by the extensive deposition of fat in the hepatocytes. Current treatments are very limited due to its unclear pathogenesis. Here, we investigated the function of circ_0057558 and m...

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Bibliographic Details
Main Authors: Xi Chen, Qing-Qing Tan, Xin-Rui Tan, Shi-Jun Li, Xing-Xing Zhang
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-04090-z