Nucleolin inhibits G4 oligonucleotide unwinding by Werner helicase.

The Werner protein (WRNp), a member of the RecQ helicase family, is strongly associated with the nucleolus, as is nucleolin (NCL), an important nucleolar constituent protein. Both WRNp and NCL respond to the effects of DNA damaging agents. Therefore, we have investigated if these nuclear proteins in...

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Bibliographic Details
Main Authors: Fred E Indig, Ivana Rybanska, Parimal Karmakar, Chakravarty Devulapalli, Haiqing Fu, France Carrier, Vilhelm A Bohr
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3366963?pdf=render