Intermittent administration of a leucine-deprived diet is able to intervene in type 2 diabetes in db/db mice

Continuous deficiency of leucine, a member of branched chain amino acids, is able to reduce obesity and improve insulin sensitivity in mice. Intermittent fasting has been shown to be effective in intervention of metabolic disorders including diabetes. However, it is unknown whether intermittent leuc...

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Bibliographic Details
Main Authors: Siying Wei, Jingyu Zhao, Shuo Wang, Meiqin Huang, Yining Wang, Yan Chen
Format: Article
Language:English
Published: Elsevier 2018-09-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844018336351