Digital signal processing reveals circadian baseline oscillation in majority of mammalian genes.

In mammals, circadian periodicity has been described for gene expression in the hypothalamus and multiple peripheral tissues. It is accepted that 10%-15% of all genes oscillate in a daily rhythm, regulated by an intrinsic molecular clock. Statistical analyses of periodicity are limited by the small...

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Bibliographic Details
Main Authors: Andrey A Ptitsyn, Sanjin Zvonic, Jeffrey M Gimble
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0030120