Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences.

Production of Mucosally Transmissible SHIV Challenge Stocks from HIV-1 Circulating Recombinant Form 01_AE env Sequences.

Simian-human immunodeficiency virus (SHIV) challenge stocks are critical for preclinical testing of vaccines, antibodies, and other interventions aimed to prevent HIV-1. A major unmet need for the field has been the lack of a SHIV challenge stock expressing circulating recombinant form 01_AE (CRF01_...

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Bibliographic Details
Main Authors: Lawrence J Tartaglia, Hui-Wen Chang, Benjamin C Lee, Peter Abbink, David Ng'ang'a, Michael Boyd, Christy L Lavine, So-Yon Lim, Srisowmya Sanisetty, James B Whitney, Michael S Seaman, Morgane Rolland, Sodsai Tovanabutra, Jintanat Ananworanich, Merlin L Robb, Jerome H Kim, Nelson L Michael, Dan H Barouch
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-02-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4743977?pdf=render

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http://europepmc.org/articles/PMC4743977?pdf=render

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