G-CSF administration to adult mice stimulates the proliferation of microglia but does not modify the outcome of ischemic injury

G-CSF administration to adult mice stimulates the proliferation of microglia but does not modify the outcome of ischemic injury

Recent evidence suggests that adult bone marrow stem cells reduce tissue damage and promote repair following CNS ischemic injury. Since granulocyte-colony stimulating factor (G-CSF) mobilizes hematopoietic stem cells to the circulating compartment, here we tested whether administration of this drug...

Full description

Bibliographic Details
Main Authors: Alice Bartolini, Maria-Claudia Vigliani, Lorenzo Magrassi, Alessandro Vercelli, Ferdinando Rossi
Format: Article
Language:English
Published: Elsevier 2011-03-01
Series:Neurobiology of Disease
Subjects:
G-CSF
Medial cerebral artery occlusion
Hematopoietic cells
Brain repair
Cell proliferation
Bone marrow
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996110003888

Internet

http://www.sciencedirect.com/science/article/pii/S0969996110003888

Similar Items