A Bombesin-Shepherdin Radioconjugate Designed for Combined Extra- and Intracellular Targeting

A Bombesin-Shepherdin Radioconjugate Designed for Combined Extra- and Intracellular Targeting

Radiolabeled peptides which target tumor-specific membrane structures of cancer cells represent a promising class of targeted radiopharmaceuticals for the diagnosis and therapy of cancer. A potential drawback of a number of reported radiopeptides is the rapid washout of a substantial fraction of the...

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Bibliographic Details
Main Authors: Christiane A. Fischer, Sandra Vomstein, Thomas L. Mindt
Format: Article
Language:English
Published: MDPI AG 2014-05-01
Series:Pharmaceuticals
Subjects:
multifunctional radioconjugates
intra- and extracellular targeting
tumor-targeting
99mTc-tricarbonyl
bombesin
shepherdin
gastrin releasing peptide receptor
Hsp90
SPECT
Online Access:http://www.mdpi.com/1424-8247/7/6/662

Internet

http://www.mdpi.com/1424-8247/7/6/662

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