Serotonin Transporter Binding in the Human Brain After Pharmacological Challenge Measured Using PET and PET/MR

Serotonin Transporter Binding in the Human Brain After Pharmacological Challenge Measured Using PET and PET/MR

Introduction:In-vivo quantification of the serotonin transporter (SERT) guided our understanding of many neuropsychiatric disorders. A recently introduced bolus plus constant infusion protocol has been shown to allow the reliable determination of SERT binding with reduced scan time. In this work, th...

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Bibliographic Details
Main Authors: Leo R. Silberbauer, Gregor Gryglewski, Neydher Berroterán-Infante, Lucas Rischka, Thomas Vanicek, Verena Pichler, Marius Hienert, Alexander Kautzky, Cecile Philippe, Godber M. Godbersen, Chrysoula Vraka, Gregory M. James, Wolfgang Wadsak, Markus Mitterhauser, Marcus Hacker, Siegfried Kasper, Andreas Hahn, Rupert Lanzenberger
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Molecular Neuroscience
Subjects:
serotonin transporter
[11C]DASB
bolus plus infusion
PET
neuroimaging
quantification
Online Access:https://www.frontiersin.org/article/10.3389/fnmol.2019.00172/full

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https://www.frontiersin.org/article/10.3389/fnmol.2019.00172/full

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