Intracerebral haemorrhage in Down syndrome: protected or predisposed? [version 1; referees: 2 approved]

Intracerebral haemorrhage in Down syndrome: protected or predisposed? [version 1; referees: 2 approved]

Down syndrome (DS), which arises from trisomy of chromosome 21, is associated with deposition of large amounts of amyloid within the central nervous system. Amyloid accumulates in two compartments: as plaques within the brain parenchyma and in vessel walls of the cerebral microvasculature. The paren...

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Bibliographic Details
Main Authors: Lewis Buss, Elizabeth Fisher, John Hardy, Dean Nizetic, Jurgen Groet, Laura Pulford, André Strydom
Format: Article
Language:English
Published: F1000 Research Ltd 2016-05-01
Series:F1000Research
Subjects:
Animal Genetics
Cellular Death & Stress Responses
Cerebrovascular Disease
Cognitive Neurology & Dementia
Cognitive Neuroscience
Epidemiology
Immune Response
Medical Genetics
Neurobiology of Disease & Regeneration
Neurogenetics
Neuronal & Glial Cell Biology
Online Access:http://f1000research.com/articles/5-876/v1

Internet

http://f1000research.com/articles/5-876/v1

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