Microglial Scavenger Receptors and Their Roles in the Pathogenesis of Alzheimer's Disease

Alzheimer’s disease (AD) is increasing in prevalence with the aging population. Deposition of amyloid-β (Aβ) in the brain of AD patients is a hallmark of the disease and is associated with increased microglial numbers and activation state. The interaction of microglia with Aβ appears to play a dicho...

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Bibliographic Details
Main Authors: Kim Wilkinson, Joseph El Khoury
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Alzheimer's Disease
Online Access:http://dx.doi.org/10.1155/2012/489456