Protective Effects of Dihydromyricetin against •OH-Induced Mesenchymal Stem Cells Damage and Mechanistic Chemistry

Protective Effects of Dihydromyricetin against •OH-Induced Mesenchymal Stem Cells Damage and Mechanistic Chemistry

As a natural flavonoid in Ampelopsis grossedentata, dihydromyricetin (DHM, 2R,3R-3,5,7,3′,4′,5′-hexahydroxy-2,3-dihydroflavonol) was observed to increase the viability of •OH-treated mesenchymal stem cells using a MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl] assay and flow cytometry analysis. Thi...

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Bibliographic Details
Main Authors: Xican Li, Jingjing Liu, Jian Lin, Tingting Wang, Jieyuan Huang, Yongqiang Lin, Dongfeng Chen
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Molecules
Subjects:
dihydromyricetin
mesenchymal stem cells
antioxidant mechanisms
hydroxyl radical-induced
Fe2+-chelation
3–OH group
2,3-double bond
electron transfer (ET) pathway
Online Access:http://www.mdpi.com/1420-3049/21/5/604

Internet

http://www.mdpi.com/1420-3049/21/5/604

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