MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)

MSP-RON Signaling Is Activated in the Transition From Pancreatic Intraepithelial Neoplasia (PanIN) to Pancreatic Ductal Adenocarcinoma (PDAC)

Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest epithelial malignancies and remains difficult to treat. Pancreatic intraepithelial neoplasias (PanINs) represent the majority of the pre-cancer lesions in the pancreas. The PDAC microenvironment consists of activated pancreatic stellate...

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Bibliographic Details
Main Authors: Ce Li, Susan Morvaridi, Gloria Lam, Chintan Chheda, Yoshiko Kamata, Makoto Katsumata, Mouad Edderkaoui, Xiaopu Yuan, Nicholas Nissen, Stephen J. Pandol, Qiang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
MSP/MST1
RON/MST1R
matriptase
pancreas
stellate cell
pancreatic ductal adenocarcinoma
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00147/full

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https://www.frontiersin.org/article/10.3389/fphys.2019.00147/full

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