Response of Human T Cells to Tetanus Neurotoxin HCC Sub-Domain: T Cell Cytokine Production and Activation Marker Induced by HCC

Tetanus is caused by the tetanus neurotoxin (TeNT), a 150 kDa single polypeptide molecule which is cleaved into active two-chain molecules composed of a 50 kDa N-terminal light (L) and a 100 kDa C-terminal heavy (H) chains. Fragment C is further subdivided into two subdomains: the proximal HCN  sub...

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Main Authors: Maryam Ghafari-Khamene, Saeedeh Torabi-Goudarzi, Maryam Hosseini, Mostafa Haji-Fatahaliha, Sanam Sadreddini, Mehrnosh Seyfi-Najmi, Jafar Majidi, Mehdi Yousefi
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2015-10-01
Series:Iranian Journal of Allergy, Asthma and Immunology
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Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/606