Early virus-host interactions dictate the course of a persistent infection.

Many persistent viral infections are characterized by a hypofunctional T cell response and the upregulation of negative immune regulators. These events occur days after the initiation of infection. However, the very early host-virus interactions that determine the establishment of viral persistence...

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Bibliographic Details
Main Authors: Brian M Sullivan, John R Teijaro, Juan Carlos de la Torre, Michael B A Oldstone
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4287607?pdf=render