Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria.

Phase 1 study in malaria naïve adults of BSAM2/Alhydrogel®+CPG 7909, a blood stage vaccine against P. falciparum malaria.

A Phase 1 dose escalating study was conducted in malaria naïve adults to assess the safety, reactogenicity, and immunogenicity of the blood stage malaria vaccine BSAM2/Alhydrogel®+ CPG 7909. BSAM2 is a combination of the FVO and 3D7 alleles of recombinant AMA1 and MSP1(42), with equal amounts by wei...

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Bibliographic Details
Main Authors: Ruth D Ellis, Yimin Wu, Laura B Martin, Donna Shaffer, Kazutoyo Miura, Joan Aebig, Andrew Orcutt, Kelly Rausch, Daming Zhu, Anders Mogensen, Michael P Fay, David L Narum, Carole Long, Louis Miller, Anna P Durbin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3464250?pdf=render

Internet

http://europepmc.org/articles/PMC3464250?pdf=render

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