Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

Neurotoxicity of bupivacaine and liposome bupivacaine after sciatic nerve block in healthy and streptozotocin-induced diabetic mice

Abstract Background Long-acting local anaesthetics (e.g. bupivacaine hydrochloride) or sustained-release formulations of bupivacaine (e.g. liposomal bupivacaine) may be neurotoxic when applied in the setting of diabetic neuropathy. The aim of the study was to assess neurotoxicity of bupivacaine and...

Full description

Bibliographic Details
Main Authors: Liljana Markova, Nejc Umek, Simon Horvat, Admir Hadžić, Max Kuroda, Tatjana Stopar Pintarič, Vesna Mrak, Erika Cvetko
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Veterinary Research
Subjects:
Bupivacaine hydrochloride
Diabetes
Liposome bupivacaine injectable suspension
Neurotoxicity
Peripheral neuropathy
Online Access:http://link.springer.com/article/10.1186/s12917-020-02459-4

Internet

http://link.springer.com/article/10.1186/s12917-020-02459-4

Similar Items