Cancer-Associated Fibroblast Density, Prognostic Characteristics, and Recurrence in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis

Cancer-Associated Fibroblast Density, Prognostic Characteristics, and Recurrence in Head and Neck Squamous Cell Carcinoma: A Meta-Analysis

IntroductionThe progression and clinical course of head and neck squamous cell carcinoma (HNSCC) relies on complex interactions between cancer and stromal cells in the tumor microenvironment (TME). Among the most abundant of these stromal cells are cancer-associated fibroblasts (CAFs). While their c...

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Bibliographic Details
Main Authors: Alexander M. Knops, Andrew South, Ulrich Rodeck, Ubaldo Martinez-Outschoorn, Larry A. Harshyne, Jennifer Johnson, Adam J. Luginbuhl, Joseph M. Curry
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Oncology
Subjects:
cancer-associated fibroblasts
CAF
tumor microenvironment
myofibroblast
alpha-smooth muscle actin
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.565306/full

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https://www.frontiersin.org/articles/10.3389/fonc.2020.565306/full

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