Celastrol slows the progression of early diabetic nephropathy in rats via the PI3K/AKT pathway

Abstract Background Diabetic nephropathy serves as one of the most regular microvascular complications of diabetes mellitus and is the main factor that causes end-stage renal disease and incident mortality. As the beneficial effect and minute adverse influence of Celastrol on the renal system requir...

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Bibliographic Details
Main Authors: Yusong Nie, Chengxiao Fu, Huimin Zhang, Min Zhang, Hui Xie, Xiaopei Tong, Yao Li, Zhenyan Hou, Xinrong Fan, Miao Yan
Format: Article
Language:English
Published: BMC 2020-10-01
Series:BMC Complementary Medicine and Therapies
Subjects:
AKT
Online Access:http://link.springer.com/article/10.1186/s12906-020-03050-y