Endoscopical and pathological dissociation in severe colitis induced by immune-checkpoint inhibitors

Endoscopical and pathological dissociation in severe colitis induced by immune-checkpoint inhibitors

Checkpoint inhibitors have improved the survival of patients with advanced tumors and show a manageable toxicity profile. However, auto-immune colitis remains a relevant side effect, and combinations of anti-PD1/PDL1 and anti-CTLA-4 increase its incidence and severity. Here, we report the case of a...

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Bibliographic Details
Main Authors: Carlos Eduardo de Andrea, Jose Luis Perez-Gracia, Eduardo Castanon, Mariano Ponz-Sarvise, Jose I. Echeveste, Ignacio Melero, Miguel F. Sanmamed, Maria Esperanza Rodriguez-Ruiz
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:OncoImmunology
Subjects:
colitis
immune-related adverse event
nivolumab
ipilimumab
Online Access:http://dx.doi.org/10.1080/2162402X.2020.1760676

Internet

http://dx.doi.org/10.1080/2162402X.2020.1760676

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