Mutated WT1, FLT3-ITD, and NUP98-NSD1 Fusion in Various Combinations Define a Poor Prognostic Group in Pediatric Acute Myeloid Leukemia
Acute myeloid leukemia is a life-threatening malignancy in children and adolescents treated predominantly by risk-adapted intensive chemotherapy that is partly supported by allogeneic stem cell transplantation. Mutations in the WT1 gene and NUP98-NSD1 fusion are predictors of poor survival outcome/p...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Hindawi Limited
2019-01-01
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Series: | Journal of Oncology |
Online Access: | http://dx.doi.org/10.1155/2019/1609128 |