Mutated WT1, FLT3-ITD, and NUP98-NSD1 Fusion in Various Combinations Define a Poor Prognostic Group in Pediatric Acute Myeloid Leukemia

Acute myeloid leukemia is a life-threatening malignancy in children and adolescents treated predominantly by risk-adapted intensive chemotherapy that is partly supported by allogeneic stem cell transplantation. Mutations in the WT1 gene and NUP98-NSD1 fusion are predictors of poor survival outcome/p...

Full description

Bibliographic Details
Main Authors: Naghmeh Niktoreh, Christiane Walter, Martin Zimmermann, Christine von Neuhoff, Nils von Neuhoff, Mareike Rasche, Katharina Waack, Ursula Creutzig, Helmut Hanenberg, Dirk Reinhardt
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Journal of Oncology
Online Access:http://dx.doi.org/10.1155/2019/1609128