Clinical impact of de-regulated Notch-1 and Notch-3 in the development and progression of HPV-associated different histological subtypes of precancerous and cancerous lesions of human uterine cervix.

Clinical impact of de-regulated Notch-1 and Notch-3 in the development and progression of HPV-associated different histological subtypes of precancerous and cancerous lesions of human uterine cervix.

Cervical cancer is the leading cause of cancer related deaths among women in India. Limited reports are available for Notch-1 and Notch-3 protein in cervical carcinoma, which play crucial role in cell proliferation, differentiation, and apoptosis.This study was designed to evaluate the role of Notch...

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Bibliographic Details
Main Authors: Richa Tripathi, Gayatri Rath, Poonam Jawanjal, Shweta Sharma, Pallavi Singhal, Suresh Bhambhani, Showket Hussain, Mausumi Bharadwaj
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4048181?pdf=render

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http://europepmc.org/articles/PMC4048181?pdf=render

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