Structural Modifications of the Quinolin-4-yloxy Core to Obtain New <i>Staphylococcus aureus</i> NorA Inhibitors

Structural Modifications of the Quinolin-4-yloxy Core to Obtain New <i>Staphylococcus aureus</i> NorA Inhibitors

Tackling antimicrobial resistance (AMR) represents a social responsibility aimed at renewing the antimicrobial armamentarium and identifying novel therapeutical approaches. Among the possible strategies, efflux pumps inhibition offers the advantage to contrast the resistance against all drugs which...

Full description

Bibliographic Details
Main Authors: Rolando Cannalire, Gianmarco Mangiaterra, Tommaso Felicetti, Andrea Astolfi, Nicholas Cedraro, Serena Massari, Giuseppe Manfroni, Oriana Tabarrini, Salvatore Vaiasicca, Maria Letizia Barreca, Violetta Cecchetti, Francesca Biavasco, Stefano Sabatini
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
antimicrobial resistance
NorA
efflux pump inhibitors
<i>Staphylococcus aureus</i>
scaffold hopping
quinoline
Online Access:https://www.mdpi.com/1422-0067/21/19/7037

Internet

https://www.mdpi.com/1422-0067/21/19/7037

Similar Items