Protective Effects of Total Saponins of Aralia elata (Miq.) on Endothelial Cell Injury Induced by TNF-α via Modulation of the PI3K/Akt and NF-κB Signalling Pathways

Protective Effects of Total Saponins of Aralia elata (Miq.) on Endothelial Cell Injury Induced by TNF-α via Modulation of the PI3K/Akt and NF-κB Signalling Pathways

Atherosclerosis is an arterial disease associated with inflammation. Hence, the discovery of novel therapeutic agents for suppressing inflammatory responses is urgent and vital for the treatment of atherosclerosis in cardiovascular diseases. The total saponins of Aralia elata (Miq.) Seem. (TAS) are...

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Bibliographic Details
Main Authors: Ping Zhou, Weijie Xie, Yun Luo, Shan Lu, Ziru Dai, Ruiying Wang, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
atherosclerosis
tumour necrosis factor α
endothelial cell injury
inflammation
total saponins of Aralia elata (Miq.) Seem.
apoptosis
Online Access:http://www.mdpi.com/1422-0067/20/1/36

Internet

http://www.mdpi.com/1422-0067/20/1/36

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